Project: Lonza Mono Project: Large Scale Biologics Expansion

Location: Portsmouth, NH

This 50,000 square foot expansion and retrofit project includes new modular process cleanroom suites for large scale biologics. The Cardinal Group’s extensive EPCM and modular cleanroom experience secured their invitation to participate in the preconstruction design effort.  The team also contributed to subsequent procurement and construction management activities in order to provide a complete design assist cleanroom envelope for upstream and downstream process manufacturing. This included personnel and material airlocks and support rooms. The modular process suite construction was compromised of cell culture, media prep, harvest, and a 2-stage purification (post & pre-viral).

Following the preconstruction effort, The Cardinal Group was subcontracted as the Design Assist Prime Mechanical Contractor for the following scopes of work:

  • Design and coordination
  • Procurement and installation of a modular cleanroom
  • Supporting structural steel
  • Mechanical HVAC including all piping and sheet metal
  • Plumbing
  • Testing and balancing
  • Process high purity piping
  • Passivation
  • Process instrumentation
  • Assembly of process equipment

The Cardinal Group’s proactive and results oriented track record in driving the design, in addition to the key subcontractor team partners Cardinal brought to the table, ensured a successful project in just five months. Effective BIM coordination and maximizing offsite pre-fabrication of multiple systems were key strategies to deliver this project on schedule. Construction is scheduled for on-time completion of December 2016.